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Arizona Burn Center

Research & Clinical Trials

Research is an imperative part of growing, learning and better understanding the unique needs of burn patients. Our research coordinators work in harmony with the physicians, patients and their families to investigate new and more proficient means of burn care. Current projects include studying the use of new medications, treatments and techniques geared to improving the treatment of the burn patient. Some of the burn centers research is funded through pharmacy and product companies or from public or corporate grants. Other research projects are non-funded and are specifically derived by collecting data on unique or unpublished data. All of the research done in the Arizona Burn Center is overseen and approved by the hospital Investigational Review Board. This group of physicians, scientists, pharmacists, nurses and laypersons review all studies within the hospital to ensure the safety of the patient involved in the study.

Because burn care involves more than just the physical treatment of burns, the Arizona Burn Center is actively involved in research studies that help the patient and family with the psychological trauma of the burn injury. The Research Psychologist is looking at ways to gain a better understanding and improve how patients cope with the pain and long-term effects of burn injuries. These findings are vital to the continued improvement in the care of the burn patient.

The results of all of the research studies are shared at professional meetings across the United States and even throughout the world. Moreover, many of the findings are published in professional medical and scientific journals. At all times the results are presented while maintaining complete patient confidentiality. Once again, the overall goal of the research department is to improve upon and better understand burn injuries and how better to treat the patient and the family.


Use Of Integra For Coverage Of Full-Thickness Axillary Burns. M.R. Matthews, MD, S.K. Duran, RN, K.N. Foster, MD, D.M. Caruso, MD, Presented at the 52nd Annual Meeting of the Southwestern Surgical Congress, Colorado Springs, Colorado, April, 2000.

Anhydrous Ammonia Burns: Case Report And Review Of The Literature. Craig E. Amshel, MD, Michael H. Fealk, BA., Bradley J. Phillips, MD, Marc R. Matthews, MD, Daniel M. Caruso, MD Presented at the Annual Meeting of the Southeastern Surgical Congress Conference, Orlando, Florida, February, 2000.

Toxic Epidermal Necrolysis/Steven-Johnson Syndrome: Infectious Complications Are Not Increased With Central Venous Catheters. M.R. Matthews, MD, D.M. Caruso, MD, B.J. Phillips, MD, M.L. Hover, BA., L. Csontos, Pharm.D. Presented at the 16th Annual John A. Boswick Burn and Wound Care Symposium, Maui, Hawaii, February, 1999.

A Randomized Prospective Comparative Study Of Burn Wound Cellulitis Treatment (Oral Ciprofloxcillin Versus Intravenous Ticarcillin/Clavulanate). Mazin F. AlKasspooles, MD, Bruce Jones, MD, Daniel M. Caruso, MD, Micheal Fealke, MD, Mary Ruddell, RN, William R. Schiller, MD, FACS Presented at the 16th Annual John A. Boswick Burn and Wound Care Symposium, Maui, Hawaii, February, 1999.

Successful Engraftment Of Cultured Composite Autografts Utilizing Integra, Mepitel, and Sulfamylon 5% Solution: Case Report And Technical Consideration. Bruce R. Jones, DO, Daniel M.Caruso, MD, Mara L. Hover, BA. Presented at the 16th Annual John A. Boswick Burn and Wound Care Symposium, Maui, Hawaii, February, 1999.

Closure Of Fasciotomies For Compartment Syndrome Secondary To Severe Burn And Trauma Utilizing A SkinStretching Device. Daniel M. Caruso, MD, Ryan B. Tsujimura, MD, Timothy King, MD, Dennis E. Weiland, MD, FACS, William R. Schiller, MD, FACS – Presented at the R. Adams Cowley 1lth National Trauma Symposium, Baltimore, MD, November, 1996.

Clinical Protocols:

  1. The Effectiveness Of Becaplermin In Fourth-Degree Burn Wounds. 1999 – Present.
  2. A Randomized, Prospective, Comparative Study Of Central Venous Catheter (Minocycline and Rifampin Vs. Chlorhexidine And Silver Sulfadiazine) Wound Infections On Burn Patients. 1999 – Present
  3. A Prospective Study Using Daclizumab To Enhance Allograft Incorperation. 2000 – Present.
  4. A Phase II Randomized, DoubleBlind, PlaceboControlled, MultipleDose, Parallel Group, MultiCenter Study Of The Effects Of PB005 On The Re-epithelialization Of Donor Sites In Patients With Burns Which Require Skin Grafting. 1997 – 1999.
  5. A Randomized, Controlled, Paired WithinPatient Study To Evaluate The Efficacy Of INTEGRA Artificial Skin Compared To Allograft In Preventing Skin Contractures To Joints Of Burn Wounds. 1996 – 1998.
  6. Linezolid For The Treatment Of Methicillin Resistant Staphylococcus aureus (MRSA) Infections: An Evaluator-Blinded Trial Comparing Linezolid With Vancomycin Alone And Vancomycin Followed By Oral Linezolid. 1997 – 1999


Title: The domestication of fire: The relationship between biomass fuel, fossil fuel and burns
Author(s): Albertyn R, Rode H, Millar AJ, Peck MD
Journal: Burns
Volume: 38
Issue: 6
Page Numbers: 790-795
Date: September 2012

Title: Making sense of biostatistics: Crossover trials
Author(s): Pressman, MA
Journal: Journal of Clinical Research Best Practices
Volume: 8
Issue: 8
Page Numbers:
Date: August 2012

Surgery Research Program:

The research program is a volunteer opportunity for people interested in pursuing a career in the medical field. The program focuses on research yet provides opportunities for exposure to all aspects of the surgery department through regular conferences, shadowing, and networking opportunities.  

The Maricopa Integrated Health System (MIHS) is the publicly-funded health care safety net for residents of Maricopa County. MIHS serves a racially and ethnically diverse population, many of whom face major challenges to accessing health care, such as language barriers, a lack of insurance, complex medical problems and difficult socioeconomic situations. MIHS is committed to providing culturally and linguistically competent care to all that enter its doors. 

MIHS clinical facilities include Maricopa Medical Center, a 450-bed, acute-care full-service hospital with 20,000 inpatient admissions annually; the Comprehensive Health Center, a multi-specialty ambulatory care clinic; 10 community-oriented Family Health Centers, strategically located throughout the County; and the McDowell Healthcare Clinic, serving people with HIV. 

The Arizona Burn Center, located within Maricopa Medical Center, a 450-bed acute-care, full service hospital and Level I trauma center with 20,000 inpatient admissions annually. Founded in 1965 by Dr. MacDonald Wood, the Arizona Burn Center has grown from a few beds set aside for burn care to the second busiest burn center in the nation, caring for over 900 adults and children each year. It is the regional burn center for the southwestern United States, serving children and adults from Arizona, surrounding states and Northern Mexico.  This center of excellence is a 19-bed facility, all of which can be dedicated intensive care beds, expandable to 44 beds institution-wide. The outpatient Arizona Burn Clinic serves approximately 5000 children and adults each year through five outpatient clinic rooms, a pressure garment measuring room, massage therapy and a dedicated telemedicine room. Emergency burn care is a dedicated 24 hours a day service, now available nationwide through the federal- and state-supported Arizona Burn Disaster Network. 


Give Me Some Skin...Innovations In Skin Grafting - Daniel M. Caruso, MD, FACS
Vascularized Composite Allotransplantion - Anthony A. Smith, MD
It's hot - Dan Quan, DO FAAEM
Joint Trauma System - Col Jeffrey A. Bailey, MD, FACS
New Advances in Burn Plastic Surgery - Salvatore Lettieri, MD, FACS
Pediatric Burn - Kote Chundu, MD
When You’re Beyond Burned... - Patrick J O’Neill, PhD, MD, FACS 

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